Monday, June 16, 2014

Describe the role of mitosis in maintaining genetic stability.

  1. Produces two nuclei/cells with same number of chromosomes as parent cell
  2. thus daughter cells are genetically identical to parents
  3. DNA replicated via semi-conservative replication during interphase to give exact copies
  4. Each strand of parental DNA acts as template for the exact replication to form the new daughter strand
  5. through complementary base pairing
  6. In prophase, chromatin condenses to form chromosome which exists as 2 identical chromatids joined by single centromere
  7. During metaphase, sister chromatids are attached to microtubulues from either pole
  8. During anaphase, centromere divides and microtubules shorten
  9. which ensures sister chromatids are separated to opposite pole during anaphase
  10. ensuring equal distribution of chromosomes to daughter nuclei
  11. In asexual reproduction, mitosis produces genetically identical daughter cells
  12. which are clones
During anaphase, centromere divides, it doesn't split
DNA is replicated, not duplicated

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